Therapure Biomanufacturing Signs Manufacturing Deal With VBI Vaccines for Coronavirus Vaccine Candidates

VBI VACCINES | August 24, 2020

Therapure Biomanufacturing, a division of Therapure Biopharma Inc., announced today the signing of an agreement with VBI Vaccines Inc. for the manufacture of their coronavirus vaccine candidates. Therapure Biomanufacturing is an integrated contract development and manufacturing organization focused on biologic and high value therapeutics that can provide new options for patient care. Under this agreement, Therapure will be responsible for the biomanufacturing of the vaccine drug substance as well as the aseptic fill of the drug product at the Therapure facility in Mississauga, Ontario.

Mr. Safa’a Al-Rais, Therapure’s Chief Operating Officer, said: “We are delighted to partner with VBI to assist with providing an effective response to the ongoing COVID-19 pandemic through Therapure’s biomanufacturing and aseptic fill finish services for VBI’s innovative COVID-19 vaccine candidates, which utilize their flexible enveloped virus-like particle (eVLP) platform technology. Therapure prides itself on its development, clinical and commercial cGMP manufacturing expertise providing solutions for biologic therapeutics and innovative drug delivery technologies, which make a difference in patients’ lives.”

Spotlight

The traditional radial and external rotor motors in the HVAC and commercial air-moving marketplace today present manufacturers with design and manufacturing constraints: the need to accommodate large and heavy motors and stock many motor options to meet different customer specifications.


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MANUFACTURING TECHNOLOGY

WuXi Biologics Launches First Commercial Drug Product Facility for Pre-Filled Syringes

WuXi Biologics | June 06, 2022

WuXi Biologics ("WuXi Bio") (2269.HK), a global CRDMO service company, announced it has successfully launched the GMP operation of its new drug product facility DP5 located in Wuxi, China. The DP5 is the ninth operational drug product facility in the global network of WuXi Biologics. The DP5 facility features an advanced isolator filling line for continuous and steady filling services, which offers multiple volume delivery options for pre-filled syringes (PFS), including 1 mL Long, 1 mL, 2.25 mL and 3 mL. The maximum filling speed can reach 400 PFS/min to support 17 million syringes of drug products manufacturing every year. The increased manufacturing capacity at DP5 allows WuXi Biologics to provide global partners with faster and more robust end-to-end drug product services for their innovative products at different scales and stages. Compared to a traditional drug product filling line, DP5's state-of-the-art design and layout, single-use technology and automated equipment, significantly decrease the risk of contamination and maintain aseptic control required in the filling process. This process supports clients' products scale up to commercial capability and reliably delivers to patients under the highest quality standards which WuXi Biologics represents. Dr. Chris Chen, CEO of WuXi Biologics, commented, "Pre-filled syringes have emerged as one of the fastest-growing choices for biologics dosage form as our partners seek new and more convenient biologics delivery methods. The GMP operation of DP5, our first commercial drug product facility for pre-filled syringes, not only demonstrates our commitment to global partners, but also marks an important milestone for WuXi Biologics to become one of the global leaders in drug product CDMO services. We'll continue to enable our clients to advance innovative biologics towards clinical trials, regulatory approvals, and commercialization to benefit patients worldwide." About WuXi Biologics WuXi Biologics (2269.HK) is a global Contract Research, Development and Manufacturing Organization (CRDMO) offering end-to-end solutions that enable partners to discover, develop, and manufacture biologics – from concept to commercialization – for the benefit of patients worldwide. With over 10,000 skilled employees in China, the United States, Ireland, Germany, and Singapore, WuXi Biologics leverages its technologies and expertise to provide customers with efficient and cost-effective biologics discovery, development, and manufacturing solutions. As of the end of 2021, WuXi Biologics is supporting over 480 integrated client projects, including nine in commercial manufacturing. WuXi Biologics views Environmental, Social, and Governance (ESG) responsibilities as an integral component of our ethos and business strategy, and we aim to become an ESG leader in the biologics CRDMO sector. Our facilities use next-generation biomanufacturing technologies and clean energy sources. We have also established an ESG committee led by our CEO to steer the comprehensive ESG strategy and its implementation, further enhancing our commitment to sustainability.

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MANUFACTURING TECHNOLOGY

EnWave Signs Technology and Evaluation License Option Agreement with Bounty Fresh Group in the Philippines

EnWave | July 12, 2022

EnWave Corporation (TSX-V: ENW | FSE: E4U) (“EnWave”, or the "Company") announced today that it has signed a Technology Evaluation and License Option Agreement (the “Agreement”) with New Plymouth Food Inc., a part of Bounty Fresh Group, and a leading producer of protein products in Southeast Asia. Bounty will lease a 10kW Radiant Energy Vacuum (“REV™”) dehydration machine for placement at their main processing facility in the Philippines. The 10kW machine will be utilized for the development of meat, cheese, and other nutritious snacks for the Philippine market and beyond. Bounty looks to capitalize on Southeast Asia’s growing snack sector by introducing healthier, better-for-you options as well as localized flavours and ingredients which are gaining more momentum over traditional deep fried and extruded snacks. About Bounty Fresh Group- Bounty Fresh Group is a large-scale industrial agriculture company founded by the Cheng family in 1986. It began as a table egg producer and now the second-largest poultry integrator and the leading table eggs producer in the Philippines.It is the only fully-integrated poultry company that has continuously invested in company-owned facilities: Grand Parent farm, Parent Stock farm, Hatcheries, Dressing Plants, Feed Mills, and Cool-cell Broiler Complexes in the Philippines. Bounty’s poultry integration served as a platform to expand its operation in other industries such as pork products, manufacturing of other agricultural products like commercial feed and vitamins, and food take-away stores.Rolling out over 1,800 takeout outlets nationwide under the brands Chooks to Go and Uling Roasters, Bounty’s storefront operation is one of the leading take-away stores in the Philippines. About EnWave- EnWave is a global leader in the innovation and application of vacuum microwave dehydration. From its headquarters in Vancouver, BC, EnWave has developed a robust intellectual property portfolio, perfected its Radiant Energy Vacuum (REV™) technology, and transformed an innovative idea into a proven, consistent, and scalable drying solution for the food and pharmaceutical industries that vastly outperforms traditional drying methods in efficiency, capacity, product quality, and cost. With more than forty-five royalty-generating partners spanning twenty countries and five continents, EnWave’s licensed partners are creating profitable, never-before-seen snacks and ingredients, improving the quality and consistency of their existing offerings, running leaner and getting to market faster with the company’s patented technology, licensed machinery, and expert guidance. In addition, EnWave established a Limited Liability Corporation, NutraDried Food Company, LLC, to manufacture, market and sell REV-dried snack products within North America, including the popular Moon Cheese® brand, and serve as a co-manufacturer for third parties.EnWave’s strategy is to sign royalty-bearing commercial licenses with food producers who want to dry better, faster and more economical than freeze drying, rack drying and air drying. Food and ingredients companies can produce exciting new products, reach optimal moisture levels up to seven times faster, and improve product taste, texture, color and nutritional value.

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LEADERSHIP AND STRATEGY

Sight Machine recognized as a finalist of 2022 Microsoft Manufacturing & Supply Chain Partner of the Year

Sight Machine | June 29, 2022

Sight Machine Inc. today announced it has been named a finalist of the 2022 Microsoft Manufacturing & Supply Chain Partner of the Year Award. The company was honored among a global field of top Microsoft partners for demonstrating excellence in innovation and implementation of customer solutions based on Microsoft technology. Sight Machine and Microsoft have together created a set of scalable solutions and go-to-market programs for the most important tasks in the manufacturing industry. These solutions can be used immediately by both discrete and continuous process manufacturers, requiring only low initial investments and leading to a fast return on investment. Sight Machine continuously transforms and analyzes all plant data so that manufacturers can focus on improving production. This streaming platform is the breakthrough product for manufacturing data, providing every stakeholder a single, trusted and dynamically updating view of production. Purpose-built over more than a decade to convert unstructured plant data into a standardized data foundation, Sight Machine on Azure continuously analyzes all assets, data sources, and processes, from machine to enterprise level. The Microsoft Partner of the Year Awards recognize Microsoft partners that have developed and delivered outstanding Microsoft-based applications, services and devices during the past year. Awards were classified in various categories, with honorees chosen from a set of more than 3,900 submitted nominations from more than 100 countries worldwide. The Manufacturing & Supply Chain award recognizes a partner organization that excels at providing innovative and unique services or solutions based on Microsoft technologies to manufacturing & supply chain customers, demonstrating thought leadership in their industry. In 2021, Sight Machine was also named as a finalist for the Microsoft Manufacturing Partner of the Year Award. "Microsoft is leading manufacturing transformation, globally and at an industry level, and it's an honor to work closely with them, They are driving focus on the most important technical and change management problems for industry and they truly work with a partnership mindset. "Together with Microsoft and its strong ecosystem, we look forward to helping manufacturers unlock new levels of productivity and sustainability." -Jon Soberly CEO and Co-Founder Sight Machine. Additional details on the 2022 awards are available on the Microsoft Partner Network blog: https://blogs.partner.microsoft.com/mpn/congratulations-to-the-2022-microsoft-partner-of-the- year-awards-winners-and-finalists/. The complete list of categories, winners and finalists can be found at https://partner.microsoft.com/en-us/inspire/awards. About Sight Machine- Sight Machine is the data platform for manufacturing, unlocking plant data to help manufacturers improve profitability, productivity, and sustainability. Using Sight Machine's common data foundation for operations and analysis, manufacturers can make better, faster decisions for improving production performance. Sight Machine's streaming platform continuously analyzes all assets, data sources, and processes, from machine to enterprise level.

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INNOVATION

Nucor to Acquire Manufacturer of Steel Utility Structures

Nucor Corporation | June 08, 2022

Nucor Corporation (NYSE: NUE) announced today that it has entered into an agreement to acquire Summit Utility Structures LLC and related company, Sovereign Steel Manufacturing LLC, producers of metal poles and other steel structures for utility infrastructure and highway signage. These companies will become part of a new business unit, Nucor Towers & Structures, serving the utility, transportation and telecommunication sectors. While the acquired companies are ideally suited to service the markets in the Northeast part of the U.S., Nucor's plan is to establish a nationwide footprint able to service all customers throughout North America. These acquisitions continue to position Nucor as the leader in steel and downstream steel products as part of our strategy to Grow the Core, Expand Beyond and Live Our Culture. These businesses fit well into the Expand Beyond part of our strategy to acquire companies who have a direct connection to our industry, offer significant growth opportunities and enhance Nucor's position as the leading manufacturing company in the metals industry, We intend to grow these businesses to become the preferred solutions provider for utility transmission towers, substations, telecommunication towers and highway signage structures." Leon Topalian, President and Chief Executive Officer of Nucor Corporation. The market for utility infrastructure has been historically stable and is expected to enter a phase of accelerated growth due to the replacement of aging infrastructure, growth and migration of population, a focus on increasing electric grid reliability, and an increased penetration of renewable energy and energy storage. Additionally, the transition to 5G and the increased consumption of wireless data support strong market trends for telecommunication towers. The highway signage market is also continuing to see strength and is expected to benefit as departments of transportation begin to implement the recently signed federal infrastructure bill. These acquisitions create a new growth platform for our company to provide engineered solutions for utility infrastructure and construction projects. The markets for transmission and telecommunication towers are forecast to experience strong growth for decades, The creation of Nucor Towers & Structures strongly complements our plate capabilities while also adding a new dimension to our arsenal of value-added downstream products such as joists and deck, hollow structural section tubes, metal buildings, insulated metal panels, racking systems, piling and foundation solutions, and shortly, overhead doors." Chad Utermark, Executive Vice President of New Markets and Innovation. About Nucor Nucor and its affiliates are manufacturers of steel and steel products, with operating facilities in the United States, Canada and Mexico. Products produced include: carbon and alloy steel -- in bars, beams, sheet and plate; hollow structural section tubing; electrical conduit; steel racking; steel piling; steel joists and joist girders; steel deck; fabricated concrete reinforcing steel; cold finished steel; precision castings; steel fasteners; metal building systems; insulated metal panels; steel grating; and wire and wire mesh. Nucor, through The David J. Joseph Company, also brokers ferrous and nonferrous metals, pig iron and hot briquetted iron / direct reduced iron; supplies ferro-alloys; and processes ferrous and nonferrous scrap. Nucor is North America's largest recycler.

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Spotlight

The traditional radial and external rotor motors in the HVAC and commercial air-moving marketplace today present manufacturers with design and manufacturing constraints: the need to accommodate large and heavy motors and stock many motor options to meet different customer specifications.

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