Asklepios BioPharmaceutical, Inc. Launches New Portfolio Company - Actus Therapeutics, Inc.

Asklepios BioPharmaceutical, Inc. (AskBio) announced today the formation of Actus Therapeutics, Inc (Actus), a new portfolio company based on AskBio’s industry-leading gene therapy platform. Actus will benefit from AskBio’s ability to generate organ and tissue-specific single-stranded and self-complementary genome containing adeno-associated virus vectors (AAVs), the company’s manufacturing platform and managements’ experience progressing AAV gene therapy programs into the clinic. Actus will pursue therapies for multiple rare genetic diseases, and will initially focus on developing a gene therapy for Pompe Disease based on the research of Dwight Koeberl, M.D., Ph.D., professor of pediatrics and a medical genetics specialist at Duke University. AskBio is focused on expanding our current gene therapy portfolio to help patients and families with rare genetic diseases that might be treated through our proprietary gene-therapy platform,” said Sheila Mikhail, President, and CEO of AskBio and Actus. “We continue to advance the efficacy of our vectors as well as our manufacturing platform, and we are excited to be working with Dr. Dwight Koeberl and his team at Duke, with the aim of developing a new therapy for Pompe Disease.